Adverse drug effects posing sex-specific risks. Risks in this database were predicted by AwareDX to publicly available data. Over 20,000 sex risks spanning over 800 drugs and 300 side effects. Download the data or browse the repository.
OffSIDES and TwoSIDES
Drug side effects and drug-drug interactions were mined from publicly available data. OffSIDES is a database of drug side-effects that were found, but are not listed on the official FDA label. TwoSIDES is the only comprehensive database drug-drug-effect relationships. Over 3,300 drugs and 63,000 combinations connected to millions of potential adverse reactions. Read more and access […]
MADSS
Network analysis framework that identifies adverse event (AE) neighborhoods within the human interactome (protein-protein interaction network). Drugs targeting proteins within this neighborhood are predicted to be involved in mediating the AE. Links drugs to seed sets of proteins and phenotypes, like drug side-effects and diseases. A description of the algorithm is available here. Code in Python available […]