DATE

Downstream effects of targeted proteins is essential to drug design. We introduce a data-driven method named DATE, which integrates drug-target relationships with gene expression, protein-protein interaction, and pathway annotation data to connect Drugs to target pAthways by the Tissue Expression. Links drugs to tissue-specific target pathways.

467,396 connections for 1,034 drugs and 954 pathways in 259 tissues/cell lines available.